Choosing the Right Breast Imaging Test: Mammograms, MRI, and More

What Type of Mammogram Do You Need?

When it’s time for your next breast screening, you may wonder which test is best for your needs. Options include 2-D or 3-D mammograms, computer-aided digital mammography, a combination of 2-D and 3-D imaging, breast MRI, or breast ultrasound. Now, newer technologies like Molecular Breast Imaging (MBI) and the use of contrast dyes are also available. The best choice often depends on factors such as your breast density, family history, and risk factors, and your physician’s diagnosis codes help guide the radiologists’ decisions, and your insurance coverage. 

3-D Mammograms (Tomosynthesis)

3-D mammograms have gained attention as studies suggest they provide clearer and more accurate images compared to standard 2-D digital mammograms. This technology is particularly beneficial for women with dense breasts, as overlapping tissue in traditional 2-D imaging can obscure abnormalities.

  • Advantages: Improved accuracy, better visualization of dense breast tissue, and reduced recall rates.
  • Considerations: While 3-D mammograms expose women to slightly more radiation than standard mammograms, newer systems combine 2-D and 3-D imaging to lower radiation levels.

For women at average risk, mammogram screening typically begins at age 40 in the U.S., although some may start earlier based on family history or other risk factors. Shared decision-making with your gynecologist is crucial to determine the best timing and type of screening.


MRI for Breast Screening

Breast MRI provides a highly detailed 3-D view and can detect more cancers than mammography. However, it is prone to false positives, leading to additional testing and anxiety.

  • Recommended For:

    • Women with BRCA mutations or other genetic risks.
    • Those with a strong family history of breast cancer.
    • Patients with dense breast tissue where mammography is less effective.
  • Use of Contrast:
    MRI often involves the injection of a gadolinium-based contrast agent to highlight abnormalities. This enhances cancer detection but may not be suitable for individuals with kidney issues or allergies to contrast agents.

  • Insurance Preauthorization: Annual MRIs are recommended starting at age 30 for high-risk individuals but often require prior insurance approval.


Molecular Breast Imaging (MBI)

MBI is an emerging technology that uses nuclear medicine and an injected dye to detect tumors, particularly in dense breast tissue.

  • Advantages:

    • Increased cancer detection rates in dense breasts (from 1.9 to 8.8 per 1,000 women in studies).
    • Can be used as a supplement to mammograms.
  • Considerations:
    MBI involves exposure to a small amount of radiation and requires a contrast injection, which may not be suitable for everyone.


When Are Blood Tests Used in Breast Screening?

Blood tests are not standard in routine breast cancer screening but may play a role in assessing risk or monitoring.

  • BRCA Testing: Blood tests can identify genetic mutations such as BRCA1 or BRCA2, which significantly increase breast cancer risk.
  • Tumor Markers: In patients with a breast cancer diagnosis, blood tests for tumor markers (e.g., CA 15-3, CA 27.29) may be used to monitor response to treatment or detect recurrence.
  • Future Potential: Research is ongoing into blood-based “liquid biopsies” that could identify cancer-related biomarkers for earlier detection.

Understanding Your Risk Factors

Women at higher risk of breast cancer may require advanced imaging or supplemental tests like MRI or MBI. Factors increasing risk include:

  • Dense breasts (on physical exam or mammogram).
  • Genetic mutations (e.g., BRCA, GeneType testing).
  • Prior abnormal mammograms or ultrasounds.
  • History of breast lumps or very cystic breasts.
  • Strong family history or personal history of breast cancer.
  • Early menarche, late menopause, or older age at first pregnancy.
  • Lifestyle factors: obesity, smoking, increased alcohol consumption, lack of exercise, or not breastfeeding.

Take Charge of Your Breast Health

Mammograms detect anatomical changes, but they do not provide information on hormone levels or overall breast physiology. To maximize breast health:

  1. Discuss your risk factors and screening options with your gynecologist.
  2. Consider advanced imaging if you have dense breasts or other risk factors.
  3. Stay informed about newer technologies like DBT, MBI, or contrast-enhanced MRI.

At www.womenshealthpractice.com, we offer yearly breast exams, help you choose the right tests, and discuss genetic screening or other therapies tailored to your needs. With a personalized approach, you can confidently navigate your options and focus on early detection and prevention.